Welcome to SNPfold

 

Welcome to the SNPfold server website. SNPfold is an algorithm published in Halvorsen et al. 2010 that computes the potential effect of Single Nucleotide Polymorphisms (SNPs) on RNA structure. For a better understanding of how SNPfold works, as well as how to operate it, refer to the FAQ or Halvorsen et al. 2010. A version of SNPfold that can be installed and ran locally using python can be found here.

Below please enter your RNA sequence and SNPs. SNPfold will convert DNA to RNA (i.e. any T's will be considered U's). This should be the full length RNA transcript you are interested in studying. Please note that long sequences (over 2000 nucleotides may take several minutes to compute).